Here in the US, we’re six years behind in getting the brain tumor database completed, and currently the best data are from 1999. By the time you see any data showing an increase, the ticking time bomb is set. Epidemic curve projections indicate that in 2006, we can expect to see 40,000 to 50,000 cases of brain and eye cancer. This is based on published peer-reviewed studies that allow calculation of risk and construction of epidemic curves. By 2010, says Dr. Carlo, expect that number to be between 400,000 and 500,000 new cases worldwide. “This means we’re on the beginning curve of an epidemic, with epidemic defined as a change in the occurrence of a disease that is so dramatic in its increase that it portends serious public health consequences,” says Dr. Carlo.